Ticks are the leading vector of disease for animals, and rank second for humans. Lyme disease, the best-known tick-borne illness, is caused by a bacterium. Tests have been conducted on an innovative vaccine targeting the tick microbiota, with a view to reducing tick infection by this bacterium. This work was carried out by INRAE in collaboration with ANSES and the Alfort National Veterinary School, and the results were published in the journal Microbiome on 24 July.